Prenatal Testing Workflows (NIPT) | Plasma Preparation

--- Kits, Raw materials, Automated machines ---

Prenatal testing workflows such as NIPT focus on low-input cell-free DNA from maternal plasma. The fragmented nature of cfDNA and limited starting material demand preparation systems that maintain reproducibility across batches.

This page presents plasma-focused preparation strategies supporting downstream sequencing and molecular analysis workflows in research laboratories. Relevant series and platforms are listed below.

Ⅰ. Recommended Products

Cell Free DNA/RNA Kit

IVD3182 <protocol> HiPure Circulating DNA Kit Isolation circulating DNA from 1-5ml plasma, serum, body fluids using vacuum protocol	D3180<protocol> HiPure Circulating Nucleic Acid Micro Kit Isolation circulating DNA from 0.6ml plasma, serum, body fluids
12917<protocol> MagPure Circulating DNA Rich Mini Kit Rich small fragment cfDNA from 0.6ml serum plasma, remove DNA fragments＞500bp	IVD5432<protocol> MagPure Circulating DNA Mini Kit Isolation circulating DNA from 0.2-0.6ml plasma, serum, body fluids

Columns/Magnetic Beads

C13114 HiPure cfDNA Column Set I (Centrifuge Method) Designed for circulating DNA purification from plasma and other cell-free samples, compatible with both centrifugation and vacuum workflows, with sample input up to 5 mL (3-layer GF/F, 1-layer GF/B membrance)	C13115 HiPure cfDNA Column Set Ⅱ (Vacuum Method) Designed for circulating DNA purification from plasma and other cell-free samples, compatible with both centrifugation and vacuum workflows, with sample input up to 5 mL (3-layer GF/F, 1-layer GF/B membrance)
BP<protocol> MagPure A4 XP Recover DNA from PCR & enzyme reactions (Replace Beckmen or agencourt Ampure XP) Can be used in NGS library construction	C1412<protocol> MagPure Particles G Magnetic beads for circulating/FFPE DNA/RNA isolaiton, 1-1.5um size silica beads