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Magen pre-packed kits are designed for 32/48-channel automated nucleic acid extraction systems, providing ready-to-use reagent formats for magnetic bead–based purification workflows. These kits reduce manual reagent preparation and help laboratories standardize DNA and RNA extraction across routine sample processing.
Compared with large 96-channel formats, 32/48-channel pre-packed kits provide flexible throughput for laboratories handling moderate sample volumes or mixed workflow requirements. The product range supports automated purification from whole blood, buffy coat, tissue, cells, low cell-content biological samples, plasma, serum and body fluids.
By integrating MagPure magnetic bead chemistry with automation-ready reagent formats, these kits support consistent binding, washing and elution steps across compatible 32/48-channel extraction instruments.
Precast kits are designed to simplify automated nucleic acid extraction by providing pre-configured reagent formats for 96-channel extraction systems. By reducing manual reagent preparation and supporting standardized magnetic bead processing, these kits help laboratories improve workflow consistency, throughput and operational efficiency.
Magen MagPure precast kits are developed for automated DNA and RNA purification workflows across different sample types, including whole blood, plant materials, tissue, cells, low cell-content biological samples and plasma or serum. Each format is matched to a specific automated extraction workflow, supporting binding, washing and elution steps on compatible 96-channel instruments.
These kits are suitable for laboratories that require scalable, repeatable and easy-to-operate nucleic acid preparation workflows using magnetic bead technology.
Spin column–based nucleic acid purification is widely used for DNA and RNA extraction due to its consistency and ease of use. The method is based on selective binding of nucleic acids to a silica or glass fiber matrix, followed by washing and elution.
The HiPure spin column system is organized as a structured platform covering different sample input levels, from low-input purification to large-scale DNA preparation. Column selection depends primarily on sample input volume, expected yield, and workflow requirements. Detailed specifications are provided in the product-specific Purchase Guide.
This approach enables predictable and scalable nucleic acid purification across different laboratory workflows.
Chemical reagents form the foundation of nucleic acid extraction systems, controlling cell lysis, protein denaturation, inhibitor removal and nucleic acid binding conditions. The performance of DNA and RNA purification workflows depends not only on column or magnetic bead systems, but also on the composition and quality of these core reagents.
Magen molecular biology–grade reagents are selected and quality-controlled for integration into nucleic acid workflows. Chaotropic salts such as guanidine compounds enable protein denaturation and nucleic acid binding, while detergents and surfactants support membrane disruption. Additional components are used to remove inhibitors such as polyphenols and polysaccharides, improving extraction performance from challenging samples.
By optimizing these chemical components, stable and reproducible workflows can be achieved across applications including genomic DNA extraction, RNA purification and complex sample processing.
Enzymatic processing is a core component of nucleic acid sample preparation workflows, enabling efficient lysis, protein digestion and removal of interfering biomolecules prior to purification.
Within Magen systems, enzymes are not used as standalone reagents but as integrated workflow components supporting column and magnetic bead–based purification. Proteinase K enables effective protein digestion during lysis, while RNase A and DNase I are applied to selectively remove unwanted nucleic acids. In low-input workflows, carrier RNA improves recovery by reducing adsorption loss and stabilizing nucleic acids during processing.
These enzymatic steps ensure consistent nucleic acid release, improved purity and reliable downstream performance across diverse sample types including tissue, blood, microbial samples and low-abundance inputs.
The Viral & Pathogen series from Magen supports nucleic acid preparation workflows commonly used in infectious disease research and laboratory monitoring.
These systems are designed for low-cell biological samples such as plasma, serum, swab transport media and culture supernatants, as well as more complex matrices including sputum and tissue homogenates.
Two technical platforms are available within the series:
For routine viral nucleic acid extraction from low-background samples, column systems such as HiPure Viral DNA/RNA Kit (IVD4175) are commonly used. Laboratories using automated extraction platforms may prefer magnetic bead systems such as MagPure Viral DNA/RNA Kit (IVD5412).
For more complex microbial samples or sequencing-oriented pathogen studies, broader pathogen recovery systems are available, including HiPure Pathogen DNA/RNA Kit (IVD4179) for column workflows and MagPure Pathogen DNA/RNA Enrich Kit (R6672C) designed to improve pathogen signal in sequencing preparation workflows.
Purification of microRNA and other small RNA molecules requires extraction systems capable of efficiently recovering short RNA fragments while minimizing loss during purification steps. Reliable recovery of small RNAs is essential for downstream workflows including small RNA sequencing and regulatory RNA studies.
Magen provides small RNA extraction systems based on optimized column purification chemistry and complementary RNA purification workflows capable of recovering both total RNA and microRNA fractions from biological samples including tissues and cultured cells.
Within this system, the HiPure Universal miRNA Kit (R4310) enables enrichment and separation of microRNA and larger RNA molecules from biological samples. Laboratories requiring purification of both total RNA and microRNA may also use the HiPure Liquid RNA (miRNA) Kit (R4163) or the HiPure Universal RNA Kit (R4130), which support purification of RNA together with microRNA fractions for downstream gene expression and small RNA analysis workflows.
Microbial RNA preparation is strongly influenced by sample type. Soil, stool, bacterial cultures and other environmental materials differ in cell wall structure, inhibitor background and RNA stability, requiring tailored extraction strategies for reliable RNA recovery.
Environmental samples, particularly soil and stool, often contain polysaccharides, humic substances and other contaminants that can interfere with RNA purification and compromise downstream analysis. Effective workflows therefore require both efficient cell disruption and controlled background removal to preserve RNA integrity.
Magen microbial RNA systems cover a range of sample-specific solutions, including soil, stool, bacterial and yeast RNA extraction. The workflows integrate mechanical lysis with optimized purification chemistry designed to reduce inhibitor interference while maintaining RNA stability, supporting consistent performance across variable environmental samples.
Both spin column and magnetic bead formats are available to support routine laboratory workflows as well as automated and high-throughput processing.
Select the appropriate system below based on your sample type and workflow requirements.
RNA purification from whole blood requires careful control of RNase activity and removal of inhibitory components such as hemoglobin and globin RNA. Reliable extraction systems are therefore required to maintain RNA integrity for downstream gene expression analysis and transcriptomics workflows.
Magen provides blood RNA extraction systems designed for both manual centrifuge workflows and automated magnetic bead purification platforms. These systems support RNA purification from fresh blood samples as well as preserved or frozen blood materials used in molecular analysis.
Within this system, the MagPure Blood RNA Kit (R6611) serves as the magnetic bead reference configuration for automated purification of RNA from whole blood. Laboratories performing column-based workflows may refer to the HiPure Blood RNA Kit (R4161) for routine RNA purification.
For workflows involving preserved or frozen blood samples, the MagPure Blood RNA Kit II (R6613) provides a workflow that does not require red blood cell lysis and supports RNA purification from fresh or frozen blood samples. Small-volume or low-input samples may also be processed using the MagPure Blood RNA Kit C (R6611C).
Plant RNA extraction is often complicated by polysaccharides, polyphenols and active RNases that affect RNA integrity and downstream analysis. Effective workflows require both rapid RNase inactivation and controlled removal of inhibitory compounds.
Magen plant RNA extraction systems integrate column and magnetic bead workflows to support different plant sample types and experimental requirements.
For complex or variable plant samples, including tissues rich in polyphenols and polysaccharides, optimized guanidine-based lysis combined with antioxidant protection improves RNA stability and inhibitor control. A representative system is the HiPure Plant RNA Plus Kit (R4150), which uses dual-column purification to improve RNA quality for transcriptomic applications.
For difficult or inhibitor-rich samples where standard methods result in low yield or purity, CTAB-based workflows are applied to enhance impurity removal. The HiPure HP Plant RNA Mini Kit (R4165) represents this approach, combining CTAB lysis, organic extraction and DNase digestion for improved RNA purity.
For routine plant tissues, simplified guanidine-based workflows enable efficient RNA purification for RT-PCR and gene expression analysis.
Magnetic bead–based systems extend plant RNA extraction into automated and high-throughput workflows with consistent recovery across samples.
For fruit or starch-rich tissues, phenol-based workflows remain effective for challenging sample matrices.
Laboratories can select appropriate workflows based on sample composition, throughput and downstream application requirements.
RNA purification from tissues and cultured cells requires efficient disruption of cellular structures while maintaining RNA stability throughout the extraction workflow. Reliable purification is essential for downstream applications including RT-PCR analysis, gene expression profiling and transcriptomics studies.
Magen provides tissue RNA extraction systems based on both silica membrane spin column technology and magnetic bead purification platforms. These systems allow laboratories to perform RNA purification using either manual centrifuge workflows or automated magnetic extraction instruments.
Within this system, the HiPure Total RNA Plus Kit (R4111) serves as the column-based reference configuration incorporating genomic DNA removal to improve RNA purity. For automated laboratory environments, the MagPure Universal RNA Kit (IVD3020) provides the magnetic bead workflow designed for automated RNA purification from tissues and cultured cells. Broader sample compatibility can be achieved using the MagPure Universal RNA Kit II (R6623), while routine column purification workflows may use the HiPure Total RNA Kit (R4011).
DNA and RNA cleanup is a routine step in molecular workflows, used to remove primers, enzymes, salts and other reaction components prior to downstream applications such as PCR, cloning and sequencing.
Magen provides a complete cleanup system portfolio based on silica membrane and magnetic bead technologies. All systems are developed with a focus on consistent nucleic acid recovery, stable batch performance and compatibility with diverse laboratory workflows.
Compared to extraction systems, cleanup workflows follow a similar binding principle, and selection is typically determined by sample source and processing format rather than fundamental chemistry differences.
Agarose Gel Extraction
Designed for recovery of DNA fragments from agarose gels following electrophoresis.
PCR / Enzymatic Reaction Cleanup
Used for removal of primers, nucleotides, enzymes and salts from amplification and digestion reactions.
General DNA Cleanup
Provides flexible purification and concentration of DNA across different reaction systems.
RNA Cleanup
Designed for RNA desalting, concentration and purification while maintaining RNA integrity.
For workflows requiring fragment size selection or adjustable clean-up conditions in NGS library preparation, magnetic bead-based systems offer greater flexibility than fixed clean-up kits. Related products can be found in Magen NGS Clean-Up Magnetic Bead Systems.
Microbial DNA preparation is strongly influenced by sample type. Soil, stool, bacterial cultures and other environmental materials differ in cell wall structure, inhibitor background and biomass distribution, requiring different extraction strategies for reliable DNA recovery.
Environmental samples, particularly soil and stool, often contain humic substances, polysaccharides and bile-derived compounds that can interfere with downstream enzymatic reactions. Effective workflows therefore require both efficient cell disruption and consistent control of inhibitor background to ensure reliable downstream performance.
Magen microbial DNA systems cover a range of sample-specific solutions, including soil, stool, bacterial and yeast DNA extraction. The workflows integrate mechanical lysis with adsorbent-based cleanup designed to reduce inhibitor interference while maintaining nucleic acid recovery, supporting consistent performance across variable environmental samples.
Both spin column and magnetic bead formats are available to support routine laboratory workflows as well as automated and high-throughput processing.
Select the appropriate system below based on your sample type and workflow requirements.
Plant DNA extraction is often affected by polysaccharides, polyphenols and other secondary metabolites that interfere with downstream PCR and sequencing. Effective workflows require both efficient lysis and controlled removal of these inhibitors.
Magen plant DNA extraction systems integrate column and magnetic bead platforms to support different sample types and throughput requirements.
For complex plant samples such as polyphenol-rich or inhibitor-heavy tissues, CTAB-based workflows are typically applied to improve impurity removal and DNA stability. A representative product is the HiPure HP Plant DNA Kit (D3187).
For routine plant tissues with lower inhibitor content, detergent-based lysis enables rapid DNA purification with simplified handling, supporting standard PCR and genotyping workflows.
Magnetic bead–based systems extend plant DNA extraction into automated and high-throughput environments. The MagPure Plant DNA Kit (D6351) represents this workflow.
For seed samples, dedicated workflows improve lysis efficiency and impurity control for agricultural genomics applications.
Laboratories can select appropriate workflows based on sample complexity, throughput and automation requirements.
Genomic DNA purification from tissues and heterogeneous biological samples requires efficient cell disruption and removal of proteins, lipids and other inhibitory components. Reliable extraction performance is essential for downstream workflows including PCR amplification, genotyping studies and HLA typing.
Magen provides tissue and universal DNA extraction systems based on both silica membrane spin column technology and magnetic bead purification platforms. These systems support purification from a wide range of biological samples including animal tissues, cultured cells, blood derivatives and other laboratory materials.
Within this system, the HiPure Universal DNA Kit (D3018) serves as the column-based reference configuration for genomic DNA purification from diverse biological samples. For laboratories operating automated purification platforms, the MagPure Universal DNA Kit (IVD3102) provides the magnetic bead workflow designed for automated extraction systems. Tissue-based workflows may also refer to the HiPure Tissue DNA Kit (D3121) for routine genomic DNA purification from tissue samples.
For forensic DNA workflows, specialized extraction systems are available to support trace DNA recovery from challenging materials. The HiPure Bone DNA Kit (D3124) and MagPure Forensic DNA Kit (D6359D) are designed for purification of genomic DNA from bone, hair and other forensic samples requiring efficient recovery from low-input or degraded materials.
Genomic DNA extraction from whole blood requires efficient removal of inhibitors such as hemoglobin and anticoagulants while maintaining stable DNA recovery for downstream molecular analysis. Reliable purification is therefore essential for workflows including PCR amplification, genotyping studies and HLA typing.
Magen provides blood DNA extraction systems combining silica membrane spin column technology and magnetic bead purification platforms. These systems support both centrifuge-based laboratory workflows and automated magnetic extraction instruments.
Within this system, the HiPure Blood DNA Mini Kit (D3111) serves as the column-based reference configuration for routine genomic DNA purification from whole blood. For laboratories operating automated extraction workflows, the MagPure Blood DNA Kit (D6311) provides the magnetic bead platform designed for automated purification systems.
For laboratories processing multiple biological sample types, the HiPure Universal DNA Kit (D3018) and the automated MagPure Universal DNA Kit (IVD3102) also support genomic DNA purification from whole blood together with other biological samples, allowing universal extraction workflows across different sample types.
Formalin-fixed paraffin-embedded (FFPE) tissues are among the most widely archived biological materials used in oncology research and retrospective molecular studies. Extraction of nucleic acids from these samples requires efficient reversal of formaldehyde crosslinking and recovery of fragmented DNA or RNA suitable for downstream molecular analysis.
Magen provides a set of FFPE nucleic acid extraction systems developed for these workflows. The portfolio integrates both silica membrane column technology and magnetic bead purification chemistry to support different laboratory processing formats and sample throughput requirements.
Within this platform, column-based workflows support controlled purification of genomic DNA from FFPE tissue sections, while magnetic bead technologies enable scalable nucleic acid recovery and automation-compatible processing.
Representative FFPE purification systems include:
FFPE purification systems are available for multiple nucleic acid targets, including:
For a route-level overview of Magen FFPE DNA, RNA and DNA/RNA co-extraction workflows:
👉 FFPE Nucleic Acid Extraction Workflows Explained
For product-level selection based on target analyte, purification format and downstream application:
👉 FFPE Nucleic Acid Extraction Purchase Guide
The products listed below focus on genomic DNA extraction from FFPE tissue sections.
Circulating DNA extraction from plasma or serum requires efficient recovery of short cfDNA fragments while minimizing background genomic DNA contamination. Magen provides a set of circulating DNA extraction systems developed for these workflows, combining silica membrane column technology and magnetic bead-based purification to accommodate different plasma input volumes and laboratory processing formats.
Within this system, the HiPure Circulating DNA Kit (IVD3182) represents the column-based configuration designed for controlled vacuum or centrifuge workflows with plasma inputs up to 5 mL. The MagPure Circulating DNA Maxi Kit (IVD5435) serves as the magnetic bead platform for higher-volume plasma processing and automation-compatible workflows. Together these systems form the core extraction technologies within the Magen circulating DNA portfolio.
For a broader view of how these technologies fit into the Magen cfDNA workflow system, including route differences, processing logic and downstream application orientation, see the cfDNA Extraction & Enrichment Workflows page in our Technical Solutions section.
Related cfDNA Application Notes: These technical notes explain how Magen circulating DNA extraction systems connect to different plasma cfDNA research applications, including oncology ctDNA, methylation biomarkers, fragmentomics and prenatal cfDNA workflows.
Application Map · Oncology ctDNA · Methylation Biomarkers · Fragmentomics & MCED · Prenatal cfDNA
Co-isolation of DNA and RNA enables simultaneous analysis of genomic and transcriptomic information from a single sample, reducing sample consumption and improving workflow efficiency. This approach is particularly valuable in applications where sample input is limited or where direct comparison between DNA and RNA is required.
In nucleic acid extraction workflows, different co-isolation strategies are applied depending on sample type and downstream requirements. Some systems separate DNA and RNA during early lysis steps to preserve RNA integrity, while others rely on sequential binding and elution processes to maximize total nucleic acid recovery. These differences influence RNA quality, DNA yield and overall workflow flexibility.
Magen co-isolation systems are designed to support both column-based and magnetic bead–based workflows across a range of sample types including FFPE tissues, environmental samples, fibrous tissues and standard biological materials. By integrating optimized lysis chemistry and purification strategies, these systems enable reliable recovery of DNA and RNA for downstream applications such as sequencing, PCR and transcriptomic analysis.
For a route-level overview of Magen FFPE DNA, RNA and DNA/RNA co-extraction workflows:
👉 FFPE Nucleic Acid Extraction Workflows Explained
For product-level selection based on target analyte, purification format and downstream application:
👉 FFPE Nucleic Acid Extraction Purchase Guide
Automated nucleic acid extraction systems are designed to improve consistency, throughput and reproducibility in DNA and RNA purification workflows. By integrating magnetic bead–based purification with programmable processing steps, these systems enable standardized sample handling across a wide range of applications.
Magen extraction systems support flexible throughput configurations, from small-batch processing to high-throughput workflows, accommodating different laboratory requirements. These systems are compatible with multi-channel plate formats and magnetic bead consumables, enabling efficient binding, washing and elution processes in automated workflows.
Depending on application needs, different system configurations are available for low-volume, medium-volume and large-volume sample processing, including circulating nucleic acid workflows, pathogen detection, plant and tissue extraction and forensic applications. Auxiliary equipment further supports sample homogenization and liquid handling integration.
By combining automation systems with optimized reagents, consumables and workflow design, Magen provides a complete solution for nucleic acid sample preparation.
Sample preservation reagents play a critical role in maintaining nucleic acid integrity prior to extraction. During collection and transport, biological samples are exposed to nuclease activity, cellular degradation and environmental variation, which can significantly impact downstream performance.
Magen preservation reagents are designed to rapidly inactivate nucleases and stabilize nucleic acids at the point of collection. Different formulations are optimized for specific sample types, including solid tissues, liquid samples and complex matrices such as stool. These reagents support flexible storage conditions, enabling short-term room temperature transport and longer-term storage under refrigerated or frozen conditions.
By stabilizing DNA and RNA before extraction, these reagents improve consistency in downstream column and magnetic bead–based purification workflows, particularly in applications involving low-abundance or degradation-sensitive targets.
Sample stabilization is a critical upstream step in nucleic acid workflows, directly affecting downstream extraction efficiency and data reliability. During collection and transport, biological samples are exposed to nuclease activity, cellular degradation and environmental variation, which can lead to loss of DNA or RNA integrity.
Magen sample collection and preservation systems are designed to maintain nucleic acid stability across different sample types including tissue, blood, saliva, swabs and microbial samples. By controlling nuclease activity and stabilizing target molecules at the point of collection, these systems support consistent performance in downstream column and magnetic bead–based extraction workflows.
Different preservation strategies are applied depending on sample type and application, including genomic DNA stabilization, RNA protection for gene expression analysis and circulating nucleic acid preservation for liquid biopsy workflows.
Magnetic bead-based clean-up systems are widely used in post-reaction nucleic acid workflows, particularly for PCR product purification, fragment size selection and sequencing reaction clean-up. These processes help remove residual primers, enzymes, salts and other reaction components prior to downstream analysis.
Within the Magen portfolio, clean-up bead systems are developed based on PEG-mediated binding chemistry, enabling selective adsorption of nucleic acids under controlled conditions. Depending on bead configuration and workflow parameters, these systems support routine DNA/RNA purification as well as more specialized applications such as fragment size control in NGS library preparation.
Different bead configurations are optimized for distinct workflow stages, including routine clean-up, selective removal of short fragments, RNA purification and sequencing reaction purification. This allows laboratories to build flexible and reproducible workflows across molecular biology and sequencing applications while maintaining compatibility with both manual handling and automated platforms.
Magnetic bead materials provide a flexible platform for nucleic acid purification across a wide range of laboratory workflows, particularly where scalability, automation compatibility and adjustable binding conditions are required.
Within the Magen sample preparation portfolio, magnetic beads are engineered with defined surface chemistries, particle size distributions and magnetic response profiles to support DNA and RNA binding under chaotropic or PEG-mediated conditions. Silica-based particles are commonly used for nucleic acid extraction from routine, low-input or fragmented samples, while carboxyl-coated beads are applied in clean-up, size selection and enzymatic workflows such as NGS library preparation.
Different bead types are optimized for specific processing conditions, including sample input volume, nucleic acid abundance and fragment characteristics. This enables laboratories to select appropriate materials for applications ranging from general DNA/RNA isolation to circulating DNA workflows and post-extraction processing.
All magnetic bead systems are compatible with both manual protocols and automated platforms, supporting consistent performance across diverse laboratory environments.
Automated nucleic acid extraction systems rely on standardized consumables to ensure reproducibility and throughput. Deep well plates and tip combs serve as essential components in magnetic bead–based workflows, enabling liquid handling, binding, washing and elution steps across multi-channel platforms.
Magen consumables are designed for compatibility with common automated extraction systems, including 32-, 48- and 96-channel platforms. Manufactured from high-quality polypropylene and tested for DNase/RNase-free conditions, these products support reliable DNA and RNA purification while minimizing contamination risk.
Different plate formats and well geometries are available to accommodate various workflow requirements, including sample processing, storage and elution. Tip comb systems enable efficient magnetic bead transfer and washing during automated extraction procedures.
Plasmid DNA preparation is selected mainly by workflow requirements rather than sample type. In practical laboratory work, the key factors usually include plasmid copy number, endotoxin requirement, culture input, and whether the workflow is manual, high-throughput, or automation-oriented.
Magen provides a structured plasmid DNA extraction portfolio based on column and magnetic bead systems, covering both standard plasmid preparation and low-endotoxin workflows for higher-purity applications. Different products in the series are positioned for different culture inputs and downstream requirements, from routine small-scale preparation to larger-volume processing, parallel batch handling and automation-compatible workflows.
Within the current plasmid system, HiPure Plasmid Mini Kit (P1001) serves as the standard column reference product for routine plasmid preparation, while HiPure Plasmid EF Maxi Kit B (P1156B) functions as the primary low-endotoxin column reference model for larger and more demanding EF workflows. Other products in the series extend this system toward faster clarification, broader low-endotoxin preparation, high-throughput handling, or magnetic bead-based processing.
For workflow-based product selection across standard and low-endotoxin plasmid preparation, please refer to the Plasmid DNA Kits Purchase Guide.
Mechanical lysis is a critical step in nucleic acid extraction, particularly for samples that are difficult to disrupt such as microbial cells, plant tissues and complex biological matrices. Bead-based homogenization uses controlled mechanical force to break cell walls and release nucleic acids for downstream purification.
Magen bead tubes integrate optimized homogenization beads and tube formats into a ready-to-use system for different sample types. By combining specific bead materials, sizes and compositions, these systems enable efficient disruption of bacterial, fungal, tissue and stool samples while reducing variability between experiments.
Different homogenization beads provide distinct mechanical properties: smaller beads increase surface contact for microbial lysis, while larger or high-density materials generate stronger impact for tough tissues. Pre-filled bead tubes further standardize workflows by eliminating manual bead selection and improving reproducibility across samples.
By integrating bead composition with workflow design, these systems support consistent upstream processing for column and magnetic bead–based nucleic acid extraction workflows.
High molecular weight DNA extraction requires a balance between efficient cell disruption and preservation of long DNA fragments. In practice, different sample types introduce distinct challenges: soft tissues are relatively easy to digest, while microbial and plant samples often require additional strategies to overcome cell wall structures or inhibitory compounds.
The Magen High Molecular Weight DNA system is primarily based on magnetic bead technology, allowing controlled binding and gentle handling conditions that help reduce DNA fragmentation during purification. The workflow integrates protease-based lysis, optimized binding chemistry, and multi-step washing to maintain DNA integrity while removing contaminants.
Within this system, different kits are designed for specific sample categories. Universal workflows support routine biological samples, while dedicated systems introduce targeted strategies such as enzymatic lysis for bacteria, bead-assisted disruption for fungi, and inhibitor control for plant tissues. This structured approach enables laboratories to match extraction conditions to sample characteristics without compromising DNA fragment length.
In addition to magnetic bead–based systems, Magen also provides salt-out–based DNA extraction solutions for laboratories requiring a simplified workflow and cost-controlled processing. These systems are typically used for routine genomic DNA preparation, while magnetic bead platforms are preferred when higher DNA integrity or automation compatibility is required.
The purified DNA generated from these workflows is suitable for applications where DNA integrity directly impacts performance. This includes long-read sequencing platforms such as nanopore-based analysis, genome assembly, and structural variation studies, where preservation of fragment length is critical for accurate downstream results.
Formalin-fixed paraffin-embedded (FFPE) tissues are among the most widely archived biological materials used in oncology research and retrospective molecular studies. Extraction of nucleic acids from these samples requires efficient reversal of formaldehyde crosslinking and recovery of fragmented DNA or RNA suitable for downstream molecular analysis.
Magen provides a set of FFPE nucleic acid extraction systems developed for these workflows. The portfolio integrates both silica membrane column technology and magnetic bead purification chemistry to support different laboratory processing formats and sample throughput requirements.
Within this platform, column-based workflows support controlled purification of genomic DNA from FFPE tissue sections, while magnetic bead technologies enable scalable nucleic acid recovery and automation-compatible processing.
Representative FFPE purification systems include:
FFPE purification systems are available for multiple nucleic acid targets, including:
For a route-level overview of Magen FFPE DNA, RNA and DNA/RNA co-extraction workflows:
👉 FFPE Nucleic Acid Extraction Workflows Explained
For product-level selection based on target analyte, purification format and downstream application:
👉 FFPE Nucleic Acid Extraction Purchase Guide
The products listed below focus on genomic RNA extraction from FFPE tissue sections.