Magnetic Bead Blood DNA Extraction Kit

Introduction

The MagPure Blood DNA Kit provides a magnetic bead–based workflow for purification of genomic DNA from anticoagulated whole blood samples. During extraction, DNA released from lysed blood cells is captured by magnetic particles and purified through automated washing steps, producing high-quality genomic DNA suitable for PCR amplification, genotyping analysis, and routine molecular testing.

The protocol is optimized for automated nucleic acid extraction instruments and is particularly suited for 96-channel extraction platforms, allowing efficient processing of large sample batches in clinical and research laboratories.

Within the Magen blood DNA purification portfolio, laboratories operating medium-throughput extraction systems (16–48 channels) may use the MagPure Fast Blood DNA Kit (D6310C), while column-based manual extraction workflows are available through the HiPure Blood DNA Mini Kit (D3111).

Details

Specifications

Features	Specifications
Main Functions	Isolation total DNA from 200μl whole blood
Applications	PCR, southern bolt and virus detection, etc
Purification technology	Magnetic beads technology
Process method	Manual or automatic
Sample type	Anticoagulant blood, concentrated blood, buffy coat, lymphocytes and cultured cells
Sample amount	200μl
Elution volume	≥50μl
Time per run	≤60 minutes

Principle

This product is based on the purification method of high binding magnetic particles. The sample is lysed and digested under the action of lysate and Protease. DNA is released into the lysate. After adding magnetic particles and binding solution, DNA will be adsorbed on the surface of magnetic particles, and impurities such as proteins will be removed without adsorption. The adsorbed particles were washed with washing solution to remove proteins and impurities, washed with ethanol to remove salts, and finally DNA was eluted by Elution Buffer.

Advantages

High binding force - suitable for handling DNA rich samples, such as whole blood, buffy coat, concentrated blood, etc.
Fast - polydisperse magnetic beads, fast magnetic response and short extraction time
High purity - the obtained DNA can be directly used for second-generation sequencing, PCR based detection, gene bank, etc.

Kit Contents

Contents	D631101	D631102	D631103
Purification Times	48	96	480
MagPure Particles	1.2 ml	2.5 ml	11 ml
Proteinase K	24 mg	50 mg	220 mg
Protease Dissolve Buffer	1.8 ml	5 ml	15 ml
Buffer AL	15 ml	30 ml	120 ml
Buffer GW1*	22 ml	53 ml	220 ml
Elution Buffer	15 ml	30 ml	100 ml

Prepacked Kit Contents

Cat.No	Precast Reagent	D6311-F-96
Proteinase K		50 mg
Protease Dissolve Buffer		6 ml
96-Tip		1
Sample Plate	200μl Buffer AL/Reagent DX	1
Wash 1 Plate	500μl Buffer GW1	1
Wash 2 Plate	500μl Buffer GW1	1
Wash 3 Plate	500μl Buffer GW2, 20μl MagPure Particle	1
Wash 4 Plate	500μl Buffer GW2	1
Elution Plate	80μl Elution Buffer	1

Storage and Stability

Proteinase K, MagPure Particles should be stored at 2-8°C upon arrival. However, short-term storage (up to 24 weeks) at room temperature (15-25°C) does not affect their performance. The remaining kit components can be stored dry at room temperature (15-25°C) and are stable for at least 18 months under these conditions. The entire kit can be stored at 2-8°C, but in this case buffers should be redissolved before use. Make sure that all buffers are at room temperature when used.

Purchase Guide

For guidance on selecting the most appropriate DNA extraction system based on sample type, input volume and workflow requirements:

👉 Magen Kits Selection Guide

CAT NO	PRODUCT NAME	SIZE	PRICE
D631101	MagPure Blood DNA Kit	48 preps	$99.00
D631102	MagPure Blood DNA Kit	96 preps	$174.00
D631103	MagPure Blood DNA Kit	480 preps	$746.00
D6311-F-96	MagPure Blood DNA Precast Kit (96 channel machine)	96 preps	$192.00

MagPure Blood DNA Kit

Introduction

Details

Specifications

Principle

Advantages

Kit Contents

Prepacked Kit Contents

Storage and Stability

Purchase Guide

Articles

Download

Related Products

HiPure Blood DNA Mini Kit

MagPure Blood DNA Precast Kit (96 channel machine)

Popular products

HiPure Bone DNA Kit

HiPure Plant RNA Plus Kit

MagPure Forensic DNA Kit

MagPure Pathogen DNA/RNA Enrich Kit

MagPure Universal DNA Kit

HiPure Total RNA Plus Kit

MagPure FFPE DNA/RNA Kit

HiPure FFPE DNA Kit

MagPure Circulating DNA Maxi Kit

HiPure Circulating DNA Kit

HiPure Blood DNA Mini Kit