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Purification of microRNA and other small RNA molecules requires efficient recovery of short, low-abundance RNA species while minimizing loss and degradation throughout the extraction workflow. Reliable purification is essential for downstream applications including RT-PCR analysis, miRNA profiling and small RNA sequencing.
Magen provides miRNA extraction systems based on both silica membrane spin column technology and magnetic particle purification platforms. The portfolio covers cellular samples, cell-free body fluids, circulating nucleic acids and exosome-associated nucleic acids using manual or automated workflows.
Within this system, the HiPure Universal miRNA Kit (R4310) serves as the primary MagZol-based configuration for tissues and cultured cells, while the HiPure Cell miRNA Kit (R4311) provides a complementary MagZol-free workflow. For cell-free samples, the HiPure Serum/Plasma miRNA Kit (R4314) supports cfRNA and miRNA purification, while the HiPure Circulating DNA/RNA Kit (R4316) provides a combined circulating DNA/RNA route. The MagPure Serum/Plasma miRNA Kit (R6628) provides the corresponding magnetic particle workflow, while the HiPure Exosome Nucleic Acid Kit (R4319B) is designed for exosome-specific applications.
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