Product Portfolio Update
Magen Expands Its Sample Preparation Portfolio
New food DNA extraction kits, binder-free glass fiber filters and phage DNA systems join an expanded plasmid purification portfolio, extending choices for laboratories, distributors and kit manufacturers.
Magen has introduced three new product ranges and expanded its existing plasmid DNA extraction systems. These developments address different sample matrices, purification requirements and processing formats, while extending the company’s supply of core materials for nucleic acid purification.
New Series
Food DNA Extraction: Three Routes for Different Matrices
Food processing changes both the condition of DNA and the materials that accompany it during extraction. Magen’s new food DNA series provides complementary column and magnetic bead workflows, with pretreatment options for routine foods, processed solid and semi-solid samples, and lipid-rich matrices.
HiPure Food DNA Kit
Combines CTAB lysis, Proteinase K digestion and chloroform extraction with silica spin-column purification. Two protocols accommodate 200 mg or 2 g food inputs.
HiPure Food DNA Kit II
Uses Proteinase K digestion and lysate clarification before column purification. Separate protocols address processed solid and semi-solid foods without phenol or chloroform extraction.
Explore D3169 →MagPure Food DNA Kit
Provides manual or automated purification from prepared food lysates, with dedicated pretreatment routes for edible oils, lecithin and chocolate.
D6350: a cost-effective alternative to Promega FF3750. In an internal evaluation using 160 g peanut oil spiked with 15 µg soybean DNA, the tested D6350 pretreatment approaches supported DNA recovery comparable to a workflow based on Promega FF3750 under the tested conditions. Both approaches used Magen magnetic bead purification. Competitive pricing and short supply lead times further support product evaluation and routine purchasing.
New Products
Glass Fiber Filters for Purification Kit Manufacturers
Magen has developed two binder-free glass fiber materials for manufacturers evaluating alternatives to established purification membranes. Both are made from borosilicate glass fibers without added binders and are available as sheets, custom-cut formats and pre-assembled purification columns.
| Product | Material Specifications | Development Focus |
|---|---|---|
|
Glass Fiber Filter MGB MGB-100 |
Thickness: 0.68 mm Basis weight: 145 g/m² Nominal liquid particle retention: 1.0 µm |
An alternative to Whatman GF/B and Ahlstrom 121, evaluated in four-layer mini-column configurations for DNA purification. |
|
Glass Fiber Filter C GFF-100C |
Thickness: 1.0 mm Basis weight: 275 g/m² Nominal retention rating: 1.0 µm |
An extra-thick option for nucleic acid purification, including three-layer mini-column configurations. |
Internal evaluations compared Magen membranes with Whatman GF/B in selected plasmid extraction, gel recovery and large-volume DNA purification workflows. For example, four-layer MGB columns recovered 44.4 µg plasmid DNA from 5 mL bacterial culture, compared with 43.3 µg using four-layer Whatman GF/B columns under the same tested conditions.
Competitive material pricing, custom cutting and pre-assembled column options help manufacturers evaluate both purification performance and production cost. Filter sheets and assembled columns are available as free samples for laboratory evaluation.
Expanded Portfolio
A More Complete Plasmid DNA Extraction System
Magen has expanded its plasmid portfolio across culture scale, vector copy number, endotoxin requirements and processing format. The resulting system connects routine mini-preparation with high-concentration recovery, larger-scale production and automated processing.
The portfolio includes standard molecular biology-grade and low-endotoxin workflows, with additional endotoxin-removal procedures available for selected products. Column, filter-assisted and magnetic bead formats support manual centrifugation, vacuum processing, 96-well handling and compatible automation platforms.
Different purification routes address different vector characteristics. Salt-mediated binding provides options for medium- and low-copy plasmids where RNA carryover is a concern; alcohol-mediated binding supports routine recovery; and cation-mediated selective precipitation extends preparation options for high-copy vectors requiring high total yield or concentrated recovery.
New Series
Dedicated Kits for Lambda and M13 Phage DNA
The new phage DNA series adds dedicated extraction systems for lambda double-stranded DNA and M13 single-stranded DNA. Lambda kits are available in Mini, Midi and Maxi formats, while the M13 range includes Mini, 96-well and Maxi options.
The workflows combine phage-particle recovery, lysis, impurity removal and silica membrane purification without conventional phenol/chloroform extraction or separate, time-consuming DNA precipitation procedures. These dedicated routes extend Magen’s preparation options for phage research and single-stranded DNA applications.