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Your present location:Home/Products/Raw Materials and Consumables/Magnetic Bead/DNA/RNA binding bead/MagPure Particles N
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MagPure Particles N

C1411
CAT NO PRODUCT NAME SIZE PRICE
C14110 MagPure Particles N 100 ml $599.00
C14111 MagPure Particles N 400 ml $2,199.00
C14112
MagPure Particles N
3 x 400 ml
$5,999.00
C14113
MagPure Particles N
10 x 400 ml
$15,999.00

Introduction

MagPure Particles N are optimized silica magnetic beads designed to improve nucleic acid recovery from low-input or complex biological samples. Compared with standard magnetic beads, this system enhances adsorption efficiency while maintaining comparable purity profiles.

The particles are commonly used in viral nucleic acid extraction and workflows requiring higher recovery from limited material.

Details


Specifications

Features Specifications
Concentration 70 mg/ml
Appearance Suspension of yellowish brown particles
Surface functional group Si-OH, Silanol
Dispersibility Polydisperse Amorphous
Particle size 0.2-2 μm
Preservation conditions

Room Temperature, valid for up to 2 years.

It is recommended to store in 2-8°C to prevent microbial growth.

Magnetic response speed
~60 seconds
Settling velocity
>10 minutes
High salt mediated binding
>2M guanidine isothiocyanate, DNA recovery up to 80%
Alcohol mediated binding
2M guanidine hydrochloride / isopropanol (30%), and the recovery of DNA / RNA was as high as 85%
PEG8000 mediated binding
The recovery of DNA/RNA was up to 85%
DNase/RNase
Not detected
DNA residue
<1 ppm
Recommended application
Plasmid extraction, gel DNA recovery, viral nucleic acid isolation


Principle

Highsalt mediated binding: in the solution containing 2-4M guanidine isothiocyanate, Magpure particles can selectively recover DNA molecules, and impurities such as protein polysaccharides are not adsorbed.

Alcohol mediated binding: in the solution containing guanidine salt and alcohol (>25%), Magpure particles can selectively recover DNA/RNA molecules, and proteins and other impurities are not adsorbed.

After biological samples are treated with digestive solution or lysis Buffer, DNA/RNA is released from cells, organelles and protein complexes (ribosomes and nucleosomes) into reagents. After Magpure particles and binding solution are added, DNA/RNA is adsorbed to the surface of Magpure particles to form DNA/RNA bead complex. Under the action of the magnetic field, the magnetic beads are separated and collected, and the impurities such as protein are removed with the waste liquid. After two or three steps of further cleaning, the DNA/RNA magnetic bead complex is resuspended in sterilized water or TE buffer, and the DNA/RNA falls off from the surface of the magnetic beads, so as to achieve the purpose of purification.


Ordering information

CAT.No. Product Name
Package
C14110
MagPure Particles N
100 ml
C14111
MagPure Particles N
400 ml
C14112
MagPure Particles N
3 x 400 ml
C14113
MagPure Particles N
10 x 400 ml

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