Introduction
The particles are commonly used in viral nucleic acid extraction and workflows requiring higher recovery from limited material.

| CAT NO | PRODUCT NAME | SIZE | PRICE |
| C14110 | MagPure Particles N | 100 ml | $599.00 |
| C14111 | MagPure Particles N | 400 ml | $2,199.00 |
|
C14112 |
MagPure Particles N |
3 x 400 ml |
$5,999.00 |
|
C14113 |
MagPure Particles N |
10 x 400 ml |
$15,999.00 |
The particles are commonly used in viral nucleic acid extraction and workflows requiring higher recovery from limited material.
Specifications
| Features | Specifications |
| Concentration | 70 mg/ml |
| Appearance | Suspension of yellowish brown particles |
| Surface functional group | Si-OH, Silanol |
| Dispersibility | Polydisperse Amorphous |
| Particle size | 0.2-2 μm |
| Preservation conditions |
Room Temperature, valid for up to 2 years. It is recommended to store in 2-8°C to prevent microbial growth. |
|
Magnetic response speed |
~60 seconds |
|
Settling velocity |
>10 minutes |
|
High salt mediated binding |
>2M guanidine isothiocyanate, DNA recovery up to 80% |
|
Alcohol mediated binding |
2M guanidine hydrochloride / isopropanol (30%), and the recovery of DNA / RNA was as high as 85% |
|
PEG8000 mediated binding |
The recovery of DNA/RNA was up to 85% |
|
DNase/RNase |
Not detected |
|
DNA residue |
<1 ppm |
|
Recommended application |
Plasmid extraction, gel DNA recovery, viral nucleic acid isolation |
Principle
Highsalt mediated binding: in the solution containing 2-4M guanidine isothiocyanate, Magpure particles can selectively recover DNA molecules, and impurities such as protein polysaccharides are not adsorbed.
Alcohol mediated binding: in the solution containing guanidine salt and alcohol (>25%), Magpure particles can selectively recover DNA/RNA molecules, and proteins and other impurities are not adsorbed.
After biological samples are treated with digestive solution or lysis Buffer, DNA/RNA is released from cells, organelles and protein complexes (ribosomes and nucleosomes) into reagents. After Magpure particles and binding solution are added, DNA/RNA is adsorbed to the surface of Magpure particles to form DNA/RNA bead complex. Under the action of the magnetic field, the magnetic beads are separated and collected, and the impurities such as protein are removed with the waste liquid. After two or three steps of further cleaning, the DNA/RNA magnetic bead complex is resuspended in sterilized water or TE buffer, and the DNA/RNA falls off from the surface of the magnetic beads, so as to achieve the purpose of purification.
Ordering information
| CAT.No. |
Product Name |
Package |
|
C14110 |
MagPure Particles N |
100 ml |
|
C14111 |
MagPure Particles N |
400 ml |
|
C14112 |
MagPure Particles N |
3 x 400 ml |
|
C14113 |
MagPure Particles N |
10 x 400 ml |
→ Suitable for large-volume cfDNA workflows requiring higher total recovery
→ Designed for small-volume circulating DNA and fragmented DNA samples
→ General-purpose magnetic beads for routine nucleic acid extraction
For full comparison across all magnetic bead systems, refer to the Magnetic Bead Selection Guide.
D6381
D3141F
D3124
R4150
D6359D
R6672C
IVD4179
R4165
IVD3102
D3018
IVD5412
IVD4175
R6611
R4310
IVD3020
R4111
R6327
D6364
D3142
D3146
D6351
D3187
D3126
IVD5435
IVD3182
D6311
D3111