MagPure FFPE RNA Kit enables purification of RNA from paraffin-embedded tissue samples using magnetic bead adsorption technology. Magnetic particle separation provides flexible processing for laboratories handling multiple FFPE samples or integrating nucleic acid extraction with automated liquid handling systems.

Magnetic bead workflows also simplify handling of fragmented RNA molecules typically present in archived FFPE tissues.

For column-based RNA purification workflows see HiPure FFPE RNA Kit - R4143.

Laboratories requiring simultaneous purification of DNA and RNA from FFPE tissues may refer to MagPure FFPE DNA/RNA Kit - R6327.

Specifications

Principle

This product is based on the purification method of high binding magnetic particles. The sample is lysed and digested under the action of lysate and Protease. DNA is released into the lysate. After adding magnetic particles and binding solution, DNA will be adsorbed on the surface of magnetic particles, and impurities such as proteins will be removed without adsorption. The adsorbed particles were washed with washing solution to remove proteins and impurities, washed with ethanol to remove salts, and finally DNA was eluted by Elution Buffer.

Advantages

• Fast - several samples can be extracted in 120 minutes by column method
• Safe - no phenol chloroform extraction required

Kit Contents

Storage and Stability

Proteinase K and MagBind Particles should be stored at 2–8°C upon arrival. DNase I should bestored at -20°C. However, short-term storage (DNase I up to 1 weeks, Proteinase K and MagBind Particles up to 8 weeks) at room temperature (15–25°C) does not affect their performance. The remaining kit components can be stored at room temperature (15–25°C) and are stable for at least 18 months under theseconditions.

For guidance on selecting the most appropriate FFPE nucleic acid extraction system based on target analyte, workflow format and downstream application requirements:

👉 FFPE Nucleic Acid Extraction Purchase Guide

For a broader technical overview of FFPE DNA, RNA and DNA/RNA co-extraction workflow routes, processing logic and application-oriented route design:

👉 FFPE Nucleic Acid Extraction Workflows Explained

For detailed workflow structure, estimated processing time and route-specific handling logic across representative FFPE workflows: