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Selection Guide by Sample Type


Selecting the appropriate nucleic acid extraction system requires balancing sample type, input volume and downstream application requirements such as PCR, qPCR or next-generation sequencing (NGS). Different sample matrices introduce distinct challenges, including low nucleic acid abundance, inhibitor presence or sample variability, which directly influence method selection.

Magen provides a comprehensive portfolio of sample preparation solutions based on silica membrane and magnetic bead technologies, supporting both manual and automated workflows. All systems are developed with a focus on consistent performance across diverse biological samples.

This guide is designed to help laboratories and distributors quickly identify suitable Magen kits based on sample type and processing requirements, and to navigate between column-based and magnetic bead–based workflows where appropriate.

For workflow-oriented guidance by research area, including oncology, pathogen detection and plant research, please refer to our Application pages.


Sample Type DNA RNA
Silica column technology Magnetic beads technology Silica column technology Magnetic beads technology

Cell-free

D3180 micro (0.6ml) R4316 Circulating DNA/RNA (include miRNA) (1-5ml)
D3181 mini (1ml)
IVD3182 midi (1-5ml, vaccum) IVD5432 mini (0.2-0.6ml)
D3182D midi (1-5ml, spin) ⭐IVD5435 maxi  (1-6ml)

Blood

D3018 Universal (200μl) D6310C Fast blood (200~300μl) (16/32/48 extractor)
R6611 Blood RNA (1-1.5ml blood / 0.5-1ml bone marrow / Blood-Bone marrow mixed sample)
⭐D3111 mini (<200μl) D6311 blood (<200μl) (96 extractor)
R6611C Total RNA + miRNA (<50μl whole blood)
D3113 midi (<2ml) IVD3101 micro (200μl)
R6613 Blood RNA Ⅱ(1ml fresh or frozen blood / 0.5-1ml bone marrow)(Can be used in blood preservation and transportation.)
D3115 maxi (<10ml) IVD3102 Universal (200μl)
R6628 Serum miRNA (0.3-0.5ml serum/plasma)
D3117 96 plate (<200μl)

D3125 micro (1-100μl)


Tissue

Cultured Cell

⭐D3018 Universal (<20mg/< 2 x 10^6) IVD3101 micro (1-10mg/< 1 x 10^6) IVD3020 Universal (10~20mg/ 3-5 x 10^6)
D3113 midi (<200mg/< 5 x 10^7) IVD3102 Universal (<20mg/< 2 x 10^6)
D3115 maxi (<1g/< 2 x 10^8) D6359D Forensic (<10μl)(Bone, hair, fingernail, seminal strain, ect.)
D3117 96 plate (<15g) D6314 (Compatibility with Nanopore sequencing workflow )

D3121 mini (<25mg/< 5 x 10^6)
D3125 micro (<10mg)
D3129 insect (<10mg)
• Not include miRNA
• Use two columns (gDNA remove column)
D3139 insect 96 plate (<10mg)
⭐D3124 Bone (100-200mg)
R4011 total RNA (<20mg soft tissue/< 1 x 10^7)
• Not include miRNA
• Use one column
R5111 DNA/RNA co-isolation (<30mg soft tissue/< 1 x 10^7)

FFPE

D3126 FFPE DNA
R4143 FFPE RNA IVD3022 FFPE RNA
IVD5116 DNA/RNA co-isolation
IVD4144 FFPE RNA plus (with Dnase)




• Higher DNA/RNA Yield

Plant

D6351 plant (100mg) R6641 Plant (<50mg)
D6352 seed IVD3020 Universal* (<100mg)

IVD3020B Universal B (<30mg)






• Without chloroform, routine extraction

Microbial

IVD3141 stool D5131 bacterial
R4181 bacterial R6626 stool
D3142 soil D6356 soil
R4182 yeast
D3144 stool/soil 96 plate D6364 stool R4183 soil
D3146 bacterial

R4185 stool
D3147 yeast

D3148 microbiome

Viruses

Pathogen












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